New Precomputed Neuron and Expression Pattern Similarity Scores on VFB

VFB provides precomputed NBLAST scores to assist in the discovery of 1) morphologically similar neurons within and across connectome datasets and 2) potential split-GAL4 driver lines which label neurons from connectomic datasets.

NBLAST queries can be accessed in the term info panel for individuals (neuron/split-GAL4 images) (at bottom of the example image below). The queries are only available if there are any results for that individual.

Neuron-to-neuron example match:

Neuron-to-split-GAL4 expression pattern example match:

Datasets included

VFB NBLAST scores cover all available neurons and expression patterns on VFB, including some of the largest and most comprehensive individual neuron datasets:

Single Neuron/Connectome Datasets:

• FAFB-FlyWire (v783) - FlyWire Codex - on VFB
• Male-CNS optic lobe (v1.0.1) - neuprint optic-lobe - on VFB
• FlyCircuit (1.0) - site - on VFB
• FAFB-CATMAID (all datasets on the VFB server) - CATMAID server - on VFB - search for ‘EM FAFB’
• Hemibrain (1.2.1) - neuprint hemibrain - on VFB

Split-GAL4 driver line images:

• Images provided from FlyLight Split-GAL4. New images are being added to VFB regularly.